SilkSense® PLLA

Awaken Your Natural Collagen

Discover the power of SilkSense,
your ultimate solution for natural skin rejuvenation.

"The gradual collagen growth with PLLA fillers like SilkSense offers a natural lift that lasts, with minimal inflammation—a game-changer for facial rejuvenation."
- Dr. Sarah Mess, Board-Certified Plastic Surgeon

Introducing SilkSense® - PLLA

LONG LASTING COLLAGEN BOOSTER

SilkSense – PLLA is a dermal tissue filler, composed of poly-L-lactic acid, sodium carboxy-methyl cellulose and mannitol. It is white lyophilized powder, packed in a bottle, sealed with butyl rubber stopper and aluminum-plastic cap.

It is used for deep dermis injection to stimulate collagen production and increase the volume of depressed areas and correct moderate to severe facial wrinkles.

Components: PLLA, sodium carboxy-methyl cellulose, mannitol
Specification: 150mg 5.0ml, 120mg 4.0ml, 90mg 3.0ml, 60mg 2.0ml
Use Needle: Needle no smaller than 26G needle
How to Use: Pour different sterile water according to different specification and mix well.

What is PLLA?

Poly-L-lactic acid (PLLA) is one of the few FDA-approved, safe, and reliable biodegradable synthetic biomaterials. The intermediate product of PLLA degradation is lactic acid, which ultimately undergoes self-metabolism in the body, breaking down into water and carbon dioxide. It can stimulate the natural regeneration of collagen and elastic fibers in the body, effectively improving facial sagging, wrinkles, and other skin issues.

Mechanism of PLLA

Before: Depression before treatment.

0-1 days after using: PLLA injection immediately filled in the depression.

3-4 days after using: A few days after the first treatment, the water in the material is absorbed by the body, and the depression recovered slightly.

7-14 days after using: The body’s fibrous connective tissue builds and eliminates depressions and defects are eliminated.

28 days after using: After about 4 weeks, the improvement effect can be clearly seen, but deeper depression needs further treatment.

Advantages and Why Choose SilkSense® - PLLA?

Superior Product Features and Excellent Biocompatibility

  • SilkSense® PLLA Microsphere SEM Image particle size D50: 20-50μm
  • Uniform Molecular Weight And Microsphere Particles: controlled release of polylactic acid with few side reactions.
  • Smooth Surface: Reduces irritation to the body.
  • Moderate Diameter: SilkSense® PLLA microsphere D50: 20-50μm. This particle size ensures that the particles are large enough to avoid being phagocytized by dermal macrophages or passing through capillary walls, but at the same time trigger a smaller immune response and can be easily injected with needles as thin as 26G. Provide consumers with a painless and comfortable injection experience without needle clogging and nodules.

Powerful Advantages

1 Advantage Safe: PLLA is biodegradable, can be degraded and metabolized out of the body. It is also biocompatible, well tolerated by the body and does not typically cause adverse reactions. This material has been proven safe and effective with numerous medical applications for more than 25 years.

2 Advantage Effectiveness: By stimulating natural collagen production, SilkSense® can offer long term result, enhancing improved skin elasticity and firmness over time. It is ideal for consumers 30+ who are seeking solutions for skin aging, dermal deficiencies, and sagging, particularly in areas like the cheeks, temples, and around the nasolabial lines.

3 Advantage Long-lasting Results: PLLA-based fillers provide gradual and long-lasting results compared with traditional hyaluronic acid fillers. As the body gradually breaks down PLLA, fibroblasts around injection site are activated, collagen continues to be produced. Visible enhancement and effects can be shown from 4 weeks post-treatment and lasting over 24months.

4 Advantage Versatility: SilkSense® offers different specifications to meet the needs of different consumers, targeting different severity levels of wrinkles degree. It is widely used in procedures such as facial rejuvenation, non-surgical facelifts and can be used to address various facial areas.

Better Performance - SilkSense® Collagen Booster

Compared with Control Group, after 6 months of implantation in the body, more fibroblast cells can be seen around the round granular PLLA filler in the deep dermis of the skin for Test Group, indicating the generation of new collagen. Some collagen appears coarse, enveloping the implant. There is less infiltration of inflammatory cells around the implant.

Comparison with Sculptra

Comparison Indicators SilkSense - PLLA Sculptra
Microspheres (micro structure) Particle size D50: 20-50μm 40-63μm
Shape Spherical, smooth and uniform Flaky, irregular
Specifications The volume of PLLA is used as the labeling volume — Total Volume
150mg — 405mg/vial
120mg — 324mg/vial
90mg — 243mg/vial
60mg — 162mg/vial
Various specifications, providing different reconstitution specifications for different beauty seekers
The total volume of the product as the labeling volume—The corresponding volume of PLLA 367.5mg/vial—150mg.
Only one specification
Features Complete Reconstitution time Reconstitution with sterile water for injection: 1 hour Reconstitution with sterile water for injection: 24 hours
Inflammation Mild Frequent inflammation